Basic science: (April 2009)

The Reconstruction of Science Phylogeny ∗ April 24 , 2009

We are facing a real challenge when coping with the continuous acceleration of scientific production and the increasingly changing nature of science. In this article, we extend the classical framework of co-word analysis to the study of scientific landscape evolution. Capitalizing on formerly introduced science mapping methods with overlapping clustering, we propose methods to reconstruct phylo...

NCBI News, April 2009

NCBI’s PubChem now features calculated three-dimensional conformers (3-D conformers) for a large proportion of the PubChem compound database (17 million records, 88%). In addition, conformers are clustered to provide a list of similar 3-D conformers. These similar conformers provide a more relevant and expanded set of compounds with potentially similar biological and pharmacological activity. P...

Package ‘ SASPECT ’ April 17 , 2009

Package ‘ FunCluster ’ April 17 , 2009

April 17, 2009 Version 1.09 Date 2008-06-19 Title Functional Profiling of Microarray Expression Data Author Corneliu Henegar Maintainer Corneliu Henegar Depends R (>= 2.0.0), Hmisc, cluster Description FunCluster performs a functional analysis of microarray expression data based on Gene Ontology & KEGG functional annotations. From expression data ...

Package ‘ clusterGeneration ’ April 17 , 2009

Description The package contains functions for generating random clusters, generating random covariance/correlation matrices, calculating a separation index (data and population version) for pairs of clusters or cluster distributions, and 1-D and 2-D projection plots to visualize clusters. The package also contains a function to generate random clusters based on factorial designs with factors s...